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For research use only. Not for human or veterinary use.Tirzepatide. For research use only. Not for human or veterinary use.

Tirzepatide research peptide

$82.00 – $246.00

For research use only. Not for human or veterinary use.

  • ≥99% by HPLC (lot-specific)
  • Canada fulfilment

Size

Order before 14:00 ET - ships next business day.

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Third-party lab verified

HPLC + MS

Independently tested for identity and purity

Batch
TZ-081126
Tested
August 11, 2026
Purity
99.6%

Tested by Testides

Tirzepatide

$164.00

Product description

Tirzepatide research peptide is supplied to qualified Canadian institutions as a characterized laboratory material for in vitro incretin-receptor studies. The compound is a 39-amino-acid synthetic peptide bearing a C20 fatty diacid conjugate (LY3298176).

In vitro, the diacid extends availability through albumin binding, and the peptide is used as a comparator in GIP and GLP-1 receptor signalling tests. Typical designs record receptor occupancy or second-messenger readouts in cells expressing those receptors. This listing describes receptor pharmacology in experimental systems only.

The material is offered as a lyophilized vial. Identity data (CAS 2023788-19-2, formula C225H348N48O68, molecular weight 4813.5 g/mol, PubChem CID 166567236) are listed on the specification table. Store lyophilized at −20 °C, protected from light, and handle under the receiving institution's chemical-hygiene plan.

Lots are sourced from a GMP-aligned peptide manufacturing partner and released against the stated HPLC purity for that lot (≥99% by HPLC, lot-specific). Identity, chromatographic purity, and related analytical results are documented on the lot certificate of analysis (COA). Retain the COA with the inventory record.

This listing is a research-use-only peptide offered to qualified Canadian institutions for in vitro and laboratory use. Purchasing access is limited to verified Canadian research institutions; individual consumer accounts are not accepted. It is not for human or veterinary use, is not intended for diagnostic procedures, and has not been evaluated or authorized by Health Canada as a drug, diagnostic, or medical product.

Material specifications

Fields a receiving desk can paste into an order record.

SKU
NL-TIRZ-10
Pack
10 mg lyophilized vial
Purity
≥99% by HPLC (lot-specific)
CAS
2023788-19-2
Molecular formula
C225H348N48O68
Molecular weight
4813.5 g/mol
PubChem CID
166567236
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Metabolic Research

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For research use only. Not for human or veterinary use.Semaglutide. For research use only. Not for human or veterinary use.99.5%COA

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Common questions

G protein-coupled receptors can signal through more than one downstream pathway. Willard and colleagues showed that at the GLP-1 receptor, tirzepatide favours cAMP signalling over β-arrestin recruitment, and produces less receptor internalisation as a result. That preference for one pathway over another is what biased agonism means.
No. Semaglutide is a GLP-1 analogue acting at a single receptor; tirzepatide is built on the GIP backbone and acts at both the GIP and GLP-1 receptors. SURPASS-2 compared them directly over 40 weeks in type 2 diabetes and reported greater reductions in HbA1c and body weight with tirzepatide.
The C20 fatty diacid conjugated to the peptide binds reversibly to circulating albumin, creating a slowly released reservoir that extends plasma half-life. Two Aib substitutions additionally protect the peptide from dipeptidyl peptidase-4, which clears native incretins within minutes. Both are structural features, not receptor properties.
SURMOUNT-1 randomised adults with obesity or overweight with a weight-related complication and ran for 72 weeks. The highest-dose group reached a mean body-weight reduction approaching 21%, with gastrointestinal adverse events the most commonly reported findings.
Yes. Unlike most compounds discussed in this library, tirzepatide has been through regulatory review and holds authorisations for type 2 diabetes and, in several jurisdictions, chronic weight management. Reference material supplied for laboratory work is not a medicine and is not interchangeable with an authorised product.
It is cleared by proteolytic catabolism rather than cytochrome P450 metabolism, so classical metabolic interactions are limited. The interaction that does matter is indirect: like others in its class, it slows gastric emptying, which can alter the absorption of co-administered oral drugs, most noticeably during dose escalation.