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For research use only. Not for human or veterinary use.Ipamorelin. For research use only. Not for human or veterinary use.

Ipamorelin research peptide

$37.00 – $111.00

For research use only. Not for human or veterinary use.

  • ≥99% by HPLC (lot-specific)
  • Canada fulfilment

Size

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Third-party lab verified

HPLC + MS

Independently tested for identity and purity

Batch
IPA-081026
Tested
August 10, 2026
Purity
99.5%

Tested by Testides

Ipamorelin

$74.00

Product description

Ipamorelin research peptide is supplied to qualified Canadian institutions as a characterized laboratory material for in vitro receptor-pharmacology and secretagogue-comparator studies. The compound is the synthetic pentapeptide Aib-His-D-2-Nal-D-Phe-Lys-NH2 (NNC 26-0161).

In vitro, ipamorelin is an agonist at GHS-R1a, the ghrelin receptor, and is used as a selective comparator against earlier growth-hormone secretagogues that show broader pituitary cross-reactivity in published receptor assays. Three of five residues are non-proteinogenic, which supports metabolic stability in cell-based and membrane-preparation experiments. Assay designs typically record GHS-R1a occupancy, downstream second-messenger readouts, or head-to-head selectivity versus GHRP-class ligands. This listing describes receptor pharmacology in experimental systems only.

The material is offered as a lyophilized vial. Identity data (CAS 170851-70-4, formula C38H49N9O5, molecular weight 711.9 g/mol, PubChem CID 9831659) are listed on the specification table. Store lyophilized at −20 °C, protected from light, and handle under the receiving institution's chemical-hygiene plan.

Lots are sourced from a GMP-aligned peptide manufacturing partner and released against the stated HPLC purity for that lot (≥99% by HPLC, lot-specific). Identity, chromatographic purity, and related analytical results are documented on the lot certificate of analysis (COA). Retain the COA with the inventory record.

This listing is a research-use-only peptide offered to qualified Canadian institutions for in vitro and laboratory use. Purchasing access is limited to verified Canadian research institutions; individual consumer accounts are not accepted. It is not for human or veterinary use, is not intended for diagnostic procedures, and has not been evaluated or authorized by Health Canada as a drug, diagnostic, or medical product.

Material specifications

Fields a receiving desk can paste into an order record.

SKU
NL-IPAM-10
Pack
10 mg lyophilized vial
Purity
≥99% by HPLC (lot-specific)
CAS
170851-70-4
Molecular formula
C38H49N9O5
Molecular weight
711.9 g/mol
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2
PubChem CID
9831659
For research use only. Not for human or veterinary use.IGF-1 LR3. For research use only. Not for human or veterinary use.98.9%COA

IGF-1 LR3

For research use only. Not for human or veterinary use.

Growth Axis

$158.00

For research use only. Not for human or veterinary use.CJC-1295 (with DAC). For research use only. Not for human or veterinary use.98.8%COA

CJC-1295 (with DAC)

For research use only. Not for human or veterinary use.

Growth Axis

$112.00

For research use only. Not for human or veterinary use.Tesamorelin. For research use only. Not for human or veterinary use.99.3%COA

Tesamorelin

For research use only. Not for human or veterinary use.

Growth Axis

$176.00

Common questions

No. Ipamorelin is a growth hormone secretagogue acting at GHS-R1a, the ghrelin receptor. Tesamorelin, sermorelin and both CJC-1295 variants act at the GHRH receptor - a different gene, a different receptor class, and different intracellular signalling. Grouping them together is one of the most common errors made about this axis.
Selectivity here means sparing the other pituitary axes. Earlier secretagogues such as GHRP-6, GHRP-2 and hexarelin released growth hormone but also raised prolactin, ACTH and cortisol, as Arvat and colleagues documented in humans in 1997. Raun and colleagues reported ipamorelin releasing growth hormone without those accompanying rises.
All three are GHS-R1a agonists, so the difference is not the receptor but the accompanying endocrine profile. GHRP-6 and hexarelin carry documented effects on ACTH, cortisol and prolactin; ipamorelin was characterised specifically as lacking them, which is what the word 'first selective' in its original title refers to.
Once, at Phase 2 scale. Beck and colleagues published a randomised, controlled proof-of-concept study in postoperative ileus in bowel resection patients in 2014. That programme did not result in an approved indication, and there is no completed human trial examining growth hormone outcomes.
Because GHS-R1a recognises a much shorter pharmacophore than the GHRH receptor does. Five residues suffice, three of them non-standard - α-aminoisobutyric acid and two D-configured aromatics - which supply the metabolic stability an all-L pentapeptide would lack.
Ghrelin is the endogenous ligand of the receptor ipamorelin activates. Kojima and colleagues identified it in 1999 as an acylated peptide from the stomach - three years after the receptor was cloned as an orphan, and a year after ipamorelin was published. The synthetic agonists preceded the natural hormone they mimic.